Replication Data for:

Version 1.0
Paiva Pinto, Fernando Filipe, 2025, "Replication Data for:", https://doi.org/10.82210/LPNWDJ, Repositório Polen QTY, V1
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since 2024-12-13
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Description
This dataset gathers synthetic hepatic gene expression and metabolomic data related to the polyol pathway and lipogenic pathways in Type 2 Diabetes. It includes: (1) a normalized gene expression matrix for relevant genes (e.g., ALDO1, SORD, AKR1B1, KHK, FASN, SREBF1); (2) a matrix of hepatic metabolite concentrations (e.g., sorbitol, fructose, triglycerides, glutathione, lactate, pyruvate); and (3) pathway analysis results with p-values, FDR, involved genes and direction of regulation. All data are fully synthetic and intended solely for testing research data repository platforms. (2025-01-25)
Subject Engineering and Technology
Keyword Gene Expression Profiling, Metabolomics, Liver, Polyol Pathway, Systems Biology, Omics
Notes Este dataset é inteiramente sintético e não corresponde a quaisquer medições reais de amostras biológicas. Foi construído de forma a imitar estruturas típicas de dados ómicos (matrizes de expressão génica e metabolómica, mais resultados de análise de vias) para testar funcionalidades de upload, ingestão tabular, indexação e pesquisa em repositórios de dados de investigação. Não é necessária aprovação ética para a sua utilização.
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