<?xml version='1.0' encoding='UTF-8'?><metadata xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns="http://dublincore.org/documents/dcmi-terms/"><dcterms:title>Replication Data for:</dcterms:title><dcterms:identifier>https://doi.org/10.82210/LPNWDJ</dcterms:identifier><dcterms:creator>Paiva Pinto, Fernando Filipe</dcterms:creator><dcterms:publisher>Repositório Polen QTY</dcterms:publisher><dcterms:issued>2025-11-20</dcterms:issued><dcterms:modified>2025-11-20T17:18:12Z</dcterms:modified><dcterms:description>This dataset gathers synthetic hepatic gene expression and metabolomic data related to the polyol pathway and lipogenic pathways in Type 2 Diabetes. It includes: (1) a normalized gene expression matrix for relevant genes (e.g., ALDO1, SORD, AKR1B1, KHK, FASN, SREBF1); (2) a matrix of hepatic metabolite concentrations (e.g., sorbitol, fructose, triglycerides, glutathione, lactate, pyruvate); and (3) pathway analysis results with p-values, FDR, involved genes and direction of regulation. All data are fully synthetic and intended solely for testing research data repository platforms.</dcterms:description><dcterms:subject>Engineering and Technology</dcterms:subject><dcterms:subject>Gene Expression Profiling</dcterms:subject><dcterms:subject>Metabolomics</dcterms:subject><dcterms:subject>Liver</dcterms:subject><dcterms:subject>Polyol Pathway</dcterms:subject><dcterms:subject>Systems Biology</dcterms:subject><dcterms:subject>Omics</dcterms:subject><dcterms:References>doi, http://doi.org/10.54941/ahfe1003517</dcterms:References><dcterms:date>2025-11-20</dcterms:date><dcterms:contributor>Paiva Pinto, Fernando Filipe</dcterms:contributor><dcterms:contributor>João Pereira</dcterms:contributor><dcterms:contributor>Marta Costa</dcterms:contributor><dcterms:dateSubmitted>2025-11-20</dcterms:dateSubmitted><dcterms:license>CC0 1.0</dcterms:license></metadata>