{"id":379,"identifier":"LPNWDJ","persistentUrl":"https://doi.org/10.82210/LPNWDJ","protocol":"doi","authority":"10.82210","separator":"/","publisher":"Repositório Polen QTY","publicationDate":"2025-11-20","storageIdentifier":"minio://10.82210/LPNWDJ","metadataLanguage":"en","datasetType":"dataset","datasetVersion":{"id":157,"datasetId":379,"datasetPersistentId":"doi:10.82210/LPNWDJ","storageIdentifier":"minio://10.82210/LPNWDJ","versionNumber":1,"versionMinorNumber":0,"versionState":"RELEASED","latestVersionPublishingState":"RELEASED","productionDate":"2025-11-20","lastUpdateTime":"2025-11-20T17:18:12Z","releaseTime":"2025-11-20T17:18:12Z","createTime":"2025-11-20T16:18:11Z","publicationDate":"2025-11-20","citationDate":"2025-11-20","license":{"name":"CC0 1.0","uri":"http://creativecommons.org/publicdomain/zero/1.0","iconUri":"https://licensebuttons.net/p/zero/1.0/88x31.png","rightsIdentifier":"CC0-1.0","rightsIdentifierScheme":"SPDX","schemeUri":"https://spdx.org/licenses/","languageCode":"en"},"fileAccessRequest":true,"metadataBlocks":{"citation":{"displayName":"Citation Metadata","name":"citation","fields":[{"typeName":"title","multiple":false,"typeClass":"primitive","value":"Replication Data for:"},{"typeName":"author","multiple":true,"typeClass":"compound","value":[{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Paiva Pinto, Fernando Filipe"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"Instituto Politécnico de Tomar"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"CienciaID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"7416-3D51-B1B8"}}]},{"typeName":"datasetContact","multiple":true,"typeClass":"compound","value":[{"datasetContactName":{"typeName":"datasetContactName","multiple":false,"typeClass":"primitive","value":"Paiva Pinto, Fernando Filipe"},"datasetContactAffiliation":{"typeName":"datasetContactAffiliation","multiple":false,"typeClass":"primitive","value":"Instituto Politécnico de Tomar"},"datasetContactEmail":{"typeName":"datasetContactEmail","multiple":false,"typeClass":"primitive","value":"fernando.pinto@inova.business"}}]},{"typeName":"dsDescription","multiple":true,"typeClass":"compound","value":[{"dsDescriptionValue":{"typeName":"dsDescriptionValue","multiple":false,"typeClass":"primitive","value":"This dataset gathers synthetic hepatic gene expression and metabolomic data related to the polyol pathway and lipogenic pathways in Type 2 Diabetes. It includes: (1) a normalized gene expression matrix for relevant genes (e.g., ALDO1, SORD, AKR1B1, KHK, FASN, SREBF1); (2) a matrix of hepatic metabolite concentrations (e.g., sorbitol, fructose, triglycerides, glutathione, lactate, pyruvate); and (3) pathway analysis results with p-values, FDR, involved genes and direction of regulation. All data are fully synthetic and intended solely for testing research data repository platforms."},"dsDescriptionDate":{"typeName":"dsDescriptionDate","multiple":false,"typeClass":"primitive","value":"2025-01-25"}}]},{"typeName":"subject","multiple":true,"typeClass":"controlledVocabulary","value":["Engineering and Technology"]},{"typeName":"keyword","multiple":true,"typeClass":"compound","value":[{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Gene Expression Profiling"},"keywordTermURI":{"typeName":"keywordTermURI","multiple":false,"typeClass":"primitive","value":"https://id.nlm.nih.gov/mesh/D020901"},"keywordVocabulary":{"typeName":"keywordVocabulary","multiple":false,"typeClass":"primitive","value":"MeSH"},"keywordVocabularyURI":{"typeName":"keywordVocabularyURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Metabolomics"},"keywordTermURI":{"typeName":"keywordTermURI","multiple":false,"typeClass":"primitive","value":"https://id.nlm.nih.gov/mesh/D057186"},"keywordVocabulary":{"typeName":"keywordVocabulary","multiple":false,"typeClass":"primitive","value":"MeSH"},"keywordVocabularyURI":{"typeName":"keywordVocabularyURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Liver"},"keywordTermURI":{"typeName":"keywordTermURI","multiple":false,"typeClass":"primitive","value":"https://id.nlm.nih.gov/mesh/D008099"},"keywordVocabulary":{"typeName":"keywordVocabulary","multiple":false,"typeClass":"primitive","value":"MeSH"},"keywordVocabularyURI":{"typeName":"keywordVocabularyURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Polyol Pathway"},"keywordTermURI":{"typeName":"keywordTermURI","multiple":false,"typeClass":"primitive","value":"https://www.wikidata.org/wiki/Q2565245"},"keywordVocabulary":{"typeName":"keywordVocabulary","multiple":false,"typeClass":"primitive","value":"Wikidata"},"keywordVocabularyURI":{"typeName":"keywordVocabularyURI","multiple":false,"typeClass":"primitive","value":"https://www.wikidata.org/"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Systems Biology"},"keywordTermURI":{"typeName":"keywordTermURI","multiple":false,"typeClass":"primitive","value":"https://id.nlm.nih.gov/mesh/D051153"},"keywordVocabulary":{"typeName":"keywordVocabulary","multiple":false,"typeClass":"primitive","value":"MeSH"},"keywordVocabularyURI":{"typeName":"keywordVocabularyURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Omics"},"keywordTermURI":{"typeName":"keywordTermURI","multiple":false,"typeClass":"primitive","value":"https://www.wikidata.org/wiki/Q9103"},"keywordVocabulary":{"typeName":"keywordVocabulary","multiple":false,"typeClass":"primitive","value":"Wikidata"},"keywordVocabularyURI":{"typeName":"keywordVocabularyURI","multiple":false,"typeClass":"primitive","value":"https://www.wikidata.org/"}}]},{"typeName":"publication","multiple":true,"typeClass":"compound","value":[{"publicationRelationType":{"typeName":"publicationRelationType","multiple":false,"typeClass":"controlledVocabulary","value":"References"},"publicationIDType":{"typeName":"publicationIDType","multiple":false,"typeClass":"controlledVocabulary","value":"doi"},"publicationURL":{"typeName":"publicationURL","multiple":false,"typeClass":"primitive","value":"http://doi.org/10.54941/ahfe1003517"}}]},{"typeName":"notesText","multiple":false,"typeClass":"primitive","value":"Este dataset é inteiramente sintético e não corresponde a quaisquer medições reais de amostras biológicas. Foi construído de forma a imitar estruturas típicas de dados ómicos (matrizes de expressão génica e metabolómica, mais resultados de análise de vias) para testar funcionalidades de upload, ingestão tabular, indexação e pesquisa em repositórios de dados de investigação. Não é necessária aprovação ética para a sua utilização."},{"typeName":"producer","multiple":true,"typeClass":"compound","value":[{"producerName":{"typeName":"producerName","multiple":false,"typeClass":"primitive","value":"Ana Silva"},"producerAffiliation":{"typeName":"producerAffiliation","multiple":false,"typeClass":"primitive","value":"Faculdade de Medicina"}}]},{"typeName":"productionDate","multiple":false,"typeClass":"primitive","value":"2025-11-20"},{"typeName":"contributor","multiple":true,"typeClass":"compound","value":[{"contributorType":{"typeName":"contributorType","multiple":false,"typeClass":"controlledVocabulary","value":"Researcher"},"contributorName":{"typeName":"contributorName","multiple":false,"typeClass":"primitive","value":"João Pereira"}},{"contributorType":{"typeName":"contributorType","multiple":false,"typeClass":"controlledVocabulary","value":"Data Curator"},"contributorName":{"typeName":"contributorName","multiple":false,"typeClass":"primitive","value":"Marta Costa"}}]},{"typeName":"grantNumber","multiple":true,"typeClass":"compound","value":[{"grantNumberAgency":{"typeName":"grantNumberAgency","multiple":false,"typeClass":"primitive","value":"FCT – Fundação para a Ciência e a Tecnologia"},"grantNumberValue":{"typeName":"grantNumberValue","multiple":false,"typeClass":"primitive","value":"2023/11517/PEX"}}]},{"typeName":"depositor","multiple":false,"typeClass":"primitive","value":"Paiva Pinto, Fernando Filipe"},{"typeName":"dateOfDeposit","multiple":false,"typeClass":"primitive","value":"2025-11-20"}]}},"files":[],"citation":"Paiva Pinto, Fernando Filipe, 2025, \"Replication Data for:\", https://doi.org/10.82210/LPNWDJ, Repositório Polen QTY, V1"}}