<?xml version="1.0" encoding="UTF-8"?>
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  <identifier identifierType="DOI">10.82210/VSGG1G</identifier>
  <creators>
    <creator>
      <creatorName nameType="Personal">Paiva Pinto, Fernando Filipe</creatorName>
      <givenName>Fernando Filipe</givenName>
      <familyName>Paiva Pinto</familyName>
      <affiliation>Instituto Politécnico de Tomar</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Replication Data for: Dataset3 by Researcher</title>
  </titles>
  <publisher>Repositório Polen QTY</publisher>
  <publicationYear>2025</publicationYear>
  <subjects>
    <subject>Engineering and Technology</subject>
    <subject schemeURI="https://www.nlm.nih.gov/mesh/" subjectScheme="MeSH">Gene Expression Profiling</subject>
    <subject schemeURI="https://www.nlm.nih.gov/mesh/" subjectScheme="MeSH">Metabolomics</subject>
    <subject schemeURI="https://www.nlm.nih.gov/mesh/" subjectScheme="MeSH">Liver</subject>
    <subject schemeURI="https://www.wikidata.org/" subjectScheme="Wikidata">Polyol Pathway</subject>
    <subject schemeURI="https://www.nlm.nih.gov/mesh/" subjectScheme="MeSH">Systems Biology</subject>
    <subject schemeURI="https://www.wikidata.org/" subjectScheme="Wikidata">Omics</subject>
  </subjects>
  <contributors>
    <contributor contributorType="Producer">
      <contributorName nameType="Personal">Ana Silva</contributorName>
      <givenName>Ana</givenName>
      <familyName>Silva</familyName>
      <affiliation>Faculdade de Medicina</affiliation>
    </contributor>
    <contributor contributorType="ContactPerson">
      <contributorName nameType="Personal">Paiva Pinto, Fernando Filipe</contributorName>
      <givenName>Fernando Filipe</givenName>
      <familyName>Paiva Pinto</familyName>
      <affiliation>Instituto Politécnico de Tomar</affiliation>
    </contributor>
    <contributor contributorType="Researcher">
      <contributorName nameType="Personal">João Pereira</contributorName>
      <givenName>João</givenName>
      <familyName>Pereira</familyName>
    </contributor>
    <contributor contributorType="DataCurator">
      <contributorName nameType="Personal">Marta Costa</contributorName>
      <givenName>Marta</givenName>
      <familyName>Costa</familyName>
    </contributor>
  </contributors>
  <dates>
    <date dateType="Created">2025-11-21</date>
    <date dateType="Submitted">2025-11-21</date>
    <date dateType="Available">2025-11-21</date>
  </dates>
  <resourceType resourceTypeGeneral="Dataset"/>
  <relatedIdentifiers>
    <relatedIdentifier relationType="References" relatedIdentifierType="DOI">10.54941/AHFE1003517</relatedIdentifier>
  </relatedIdentifiers>
  <version>1.0</version>
  <rightsList>
    <rights rightsURI="info:eu-repo/semantics/openAccess"/>
    <rights rightsURI="http://creativecommons.org/publicdomain/zero/1.0" rightsIdentifier="CC0-1.0" rightsIdentifierScheme="SPDX" schemeURI="https://spdx.org/licenses/" xml:lang="en">Creative Commons CC0 1.0 Universal Public Domain Dedication.</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">This dataset gathers synthetic hepatic gene expression and metabolomic data related to the polyol pathway and lipogenic pathways in Type 2 Diabetes. It includes: (1) a normalized gene expression matrix for relevant genes (e.g., ALDO1, SORD, AKR1B1, KHK, FASN, SREBF1); (2) a matrix of hepatic metabolite concentrations (e.g., sorbitol, fructose, triglycerides, glutathione, lactate, pyruvate); and (3) pathway analysis results with p-values, FDR, involved genes and direction of regulation. All data are fully synthetic and intended solely for testing research data repository platforms.</description>
    <description descriptionType="Other">Este dataset é inteiramente sintético e não corresponde a quaisquer medições reais de amostras biológicas. Foi construído de forma a imitar estruturas típicas de dados ómicos (matrizes de expressão génica e metabolómica, mais resultados de análise de vias) para testar funcionalidades de upload, ingestão tabular, indexação e pesquisa em repositórios de dados de investigação. Não é necessária aprovação ética para a sua utilização.</description>
  </descriptions>
  <fundingReferences>
    <fundingReference>
      <funderName>FCT – Fundação para a Ciência e a Tecnologia</funderName>
      <awardNumber>2023/11341/PEX</awardNumber>
    </fundingReference>
  </fundingReferences>
</resource>
